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Igktm1Rsky
Targeted Allele Detail
Nomenclature
Symbol: Igktm1Rsky
Name: immunoglobulin kappa chain complex; targeted mutation 1, Klaus Rajewsky
MGI ID: MGI:3662618
Synonyms: 3-83kappai, Igktm1Pld
Gene: Igk  Location: unknown  Genetic Position: Chr6, 30.89 cM, cytoband F1-pter
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:35357
Parent Cell Line:  E14.1TG3B1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutations:    Insertion, Intergenic deletion
 
Mutation detailsA targeting vector was used to insert a floxed neo (subsequently removed via cre mediated recombination) and a recombined Vk3-83-Jk2 region replacing J1 and J2. (J:35357)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Igk Mutation:  24 strains or lines available
References
Original:  J:35357 Pelanda R, et al., A prematurely expressed Ig kappa transgene, but not a V kappa J kappa gene segment targeted into the Ig kappa locus, can rescue B cell development in lambda 5-deficient mice. Immunity. 1996 SEP;5(3):229-239
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory