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Ube2ntm1Aki
Targeted Allele Detail
Nomenclature
Symbol: Ube2ntm1Aki
Name: ubiquitin-conjugating enzyme E2N; targeted mutation 1, Shizuo Akira
MGI ID: MGI:3655236
Synonyms: Ubc13fl
Gene: Ube2n  Location: Chr10:95515162-95545658 bp, + strand  Genetic Position: Chr10, 49.41 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112287
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neomycin resistance cassette was place upstream of exon 2 and a third loxP site was placed downstream of exon 4. (J:112287)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ube2n Mutation:  5 strains or lines available
References
Original:  J:112287 Yamamoto M, et al., Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling. Nat Immunol. 2006 Sep;7(9):962-70
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory