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Efnb1tm1Rha
Targeted Allele Detail
Summary
Symbol: Efnb1tm1Rha
Name: ephrin B1; targeted mutation 1, Ralf H Adams
MGI ID: MGI:3653699
Gene: Efnb1  Location: ChrX:98179736-98192597 bp, + strand  Genetic Position: ChrX, 43.22 cM, cytoband D
Alliance: Efnb1tm1Rha page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110732
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 2 was flanked by loxP sites and fused to a human EFNB1 cDNA with a polyA signal. Western blot detected protein from mutants. A neomycin resistance gene was removed via flipase expression. (J:110732)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 9 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Efnb1 Mutation:  15 strains or lines available
References
Original:  J:110732 Compagni A, et al., Control of skeletal patterning by ephrinB1-EphB interactions. Dev Cell. 2003 Aug;5(2):217-30
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory