Ghsr^tm2Rgs
Targeted Allele Detail

Summary

• Symbol: Ghsr^tm2Rgs
• Name: growth hormone secretagogue receptor; targeted mutation 2, Roy G Smith
• MGI ID: MGI:3653692
• Synonyms: Ghsr-IRES-tauGFP
• Gene: Ghsr Location: Chr3:27425500-27432159 bp, + strand Genetic Position: Chr3, 10.86 cM
• Alliance: Ghsr^tm2Rgs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111043
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES-tauGFP cassette was inserted into the stop codon. GFP expression was detected in mutant neurons. (J:111043)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ghsr Mutation: 29 strains or lines available

References

• Original: J:111043 Jiang H, et al., Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor/dopamine receptor subtype 1 heterodimers. Mol Endocrinol. 2006 Aug;20(8):1772-85
• All: 3 reference(s)