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Ptentm1.1Hwu
Targeted Allele Detail
Nomenclature
Symbol: Ptentm1.1Hwu
Name: phosphatase and tensin homolog; targeted mutation 1.1, Hong Wu
MGI ID: MGI:3653378
Synonyms: Pten-, Ptendelta5
Gene: Pten  Location: Chr19:32757497-32826160 bp, + strand  Genetic Position: Chr19, 28.14 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110567
Parent Cell Line:  LW1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsES cells were transiently transfected with cre recombinase for removal of floxed exon 5 from the locus. (J:110567)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pten Mutation:  36 strains or lines available
References
Original:  J:110567 Freeman D, et al., Genetic background controls tumor development in PTEN-deficient mice. Cancer Res. 2006 Jul 1;66(13):6492-6
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/24/2015
MGI 5.21
The Jackson Laboratory