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Robo1tm1.1Ljr
Targeted Allele Detail
Nomenclature
Symbol: Robo1tm1.1Ljr
Name: roundabout guidance receptor 1; targeted mutation 1.1, Linda J Richards
MGI ID: MGI:3641236
Synonyms: Robo1-
Gene: Robo1  Location: Chr16:72663149-73046095 bp, + strand  Genetic Position: Chr16, 41.08 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109478
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 5 was removed via cre-mediated recombination. RT-PCR confirmed absence of wild-type transcript in mutants. Western blot failed to detect protein. (J:109478)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Robo1 Mutation:  42 strains or lines available
References
Original:  J:109478 Andrews W, et al., Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain. Development. 2006 Jun;133(11):2243-52
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory