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Tg(tetO-APPSwInd)885Dbo
Transgene Detail
Nomenclature
Symbol: Tg(tetO-APPSwInd)885Dbo
Name: transgene insertion 885, David R Borchelt
MGI ID: MGI:3639702
Synonyms: TetAPPswe/ind line 885
Transgene: Tg(tetO-APPSwInd)885Dbo  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x C3H/HeJ)F2
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Notes
Founder line 8-85 is the highest expressing line, and is representative of a number of lines made with this construct.

References
Original:  J:109829 Jankowsky JL, et al., Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease. PLoS Med. 2005 Dec;2(12):e355
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory