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Targeted Allele Detail
Symbol: Hipk1tm1Hko
Name: homeodomain interacting protein kinase 1; targeted mutation 1, Haruhiko Koseki
MGI ID: MGI:3624126
Synonyms: Hipk1-
Gene: Hipk1  Location: Chr3:103739815-103791563 bp, - strand  Genetic Position: Chr3, 45.52 cM, cytoband F3
Germline Transmission:  Earliest citation of germline transmission: J:106931
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA targeting vector was designed to replace sequence including the start codon with a neomycin resistance gene. RT-PCR demonstrated a lack of transcript in mutants, but absence of C-terminally truncated proteins could not be concluded. (J:106931)
View phenotypes for all genotypes (concatenated display).
In Mice Carrying this Mutation: 31 assay results
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hipk1 Mutation:  40 strains or lines available
Original:  J:106931 Isono K, et al., Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals. Mol Cell Biol. 2006 Apr;26(7):2758-71
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.06
The Jackson Laboratory