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Gp5tm1Cgh
Targeted Allele Detail
Nomenclature
Symbol: Gp5tm1Cgh
Name: glycoprotein 5 (platelet); targeted mutation 1, Shaun R Coughlin
MGI ID: MGI:3623935
Synonyms: GpV-
Gene: Gp5  Location: Chr16:30307685-30310779 bp, - strand  Genetic Position: Chr16, 21.26 cM, cytoband B2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59008
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene replaced the entire locus. RT-PCR of mutant spleen failed to detect transcript. (J:59008)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Gp5 Mutation:  6 strains or lines available
References
Original:  J:59008 Kahn ML, et al., Glycoprotein V-deficient platelets have undiminished thrombin responsiveness and Do not exhibit a Bernard-Soulier phenotype. Blood. 1999 Dec 15;94(12):4112-21
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/08/2020
MGI 6.15
The Jackson Laboratory