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Nck2tm3Paw
Targeted Allele Detail
Nomenclature
Symbol: Nck2tm3Paw
Name: non-catalytic region of tyrosine kinase adaptor protein 2; targeted mutation 3, Tony Pawson
MGI ID: MGI:3623745
Synonyms: Nck2fl
Gene: Nck2  Location: Chr1:43445751-43570518 bp, + strand  Genetic Position: Chr1, 23.18 cM, cytoband C1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:107630
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 1 was flanked with loxP sites. (J:107630)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nck2 Mutation:  9 strains or lines available
Notes
ES cell line = E14-ES (J:129166).
References
Original:  J:107630 Jones N, et al., Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes. Nature. 2006 Apr 6;440(7085):818-23
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory