About   Help   FAQ
Prokr2tm1Api
Targeted Allele Detail
Nomenclature
Symbol: Prokr2tm1Api
Name: prokineticin receptor 2; targeted mutation 1, Shunichiro Matsumoto
MGI ID: MGI:3623447
Synonyms: Pkr2-
Gene: Prokr2  Location: Chr2:132337733-132385447 bp, - strand  Genetic Position: Chr2, 64.15 cM
Prokr2tm1Api/Prokr2tm1Api mice, but not Prokr1tm1Api/Prokr1tm1Api mice, display olfactory bulb malformation

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:107587
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn exon containing the ATG start codon was deleted and a neo cassette in reverse orientation was inserted. Quantitative PCR confirmed ablation of the locus. (J:107587)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prokr2 Mutation:  20 strains or lines available
References
Original:  J:107587 Matsumoto S, et al., Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4140-5
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/03/2018
MGI 6.11
The Jackson Laboratory