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Tnks2tm1.1Yjc
Targeted Allele Detail
Nomenclature
Symbol: Tnks2tm1.1Yjc
Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; targeted mutation 1.1, Y Jeffrey Chiang
MGI ID: MGI:3621924
Synonyms: Tank2-
Gene: Tnks2  Location: Chr19:36834232-36893477 bp, + strand  Genetic Position: Chr19, 31.96 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:106918
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exon 1 was removed via cre-mediated excision. RT-PCR failed to detect transcript in mutants. (J:106918)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tnks2 Mutation:  29 strains or lines available
References
Original:  J:106918 Chiang YJ, et al., Generation and characterization of telomere length maintenance in tankyrase 2-deficient mice. Mol Cell Biol. 2006 Mar;26(6):2037-43
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory