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Tolliptm1Kbns
Targeted Allele Detail
Nomenclature
Symbol: Tolliptm1Kbns
Name: toll interacting protein; targeted mutation 1, Kimberly Burns
MGI ID: MGI:3619521
Synonyms: Tollip-
Gene: Tollip  Location: Chr7:141874813-141918507 bp, - strand  Genetic Position: Chr7, 87.34 cM, cytoband F5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105514
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance cassette replaced exon 1, which contains the start codon. (J:105514)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tollip Mutation:  6 strains or lines available
References
Original:  J:105514 Didierlaurent A, et al., Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide. Mol Cell Biol. 2006 Feb;26(3):735-42
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory