H2-K^bm29
Spontaneous Allele Detail

Summary

• Symbol: H2-K^bm29
• Name: histocompatibility 2, K region; b haplotype mutation 29
• MGI ID: MGI:3618265
• Gene: H2-K Location: unknown Genetic Position: Chr17, Syntenic

Mutation origin

• Strain of Origin: (C3.CAS3(R4) x C57BL/6)F2

Mutation description

• Allele Type: Spontaneous
• Mutation: Nucleotide substitutions
• Mutation details: The bm29 sequence differs from the parental sequence by two nucleotide substitutions at codon 89, resulting in a lysine to alanine substitution. This mutation is thought to have arised by a gene conversion-like event. (J:11499)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any H2-K Mutation: 31 strains or lines available

Notes

Genbank ID for this allele: M34542

References

• Original: J:11499 Horton RM, et al., Characterization of the spontaneous mutant H-2Kbm29 indicates that gene conversion in H-2 occurs at a higher frequency than detected by skin grafting. J Immunol. 1991 Nov 1;147(9):3180-4
• All: 2 reference(s)