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Tdo2chky
Spontaneous Allele Detail
Nomenclature
Symbol: Tdo2chky
Name: tryptophan 2,3-dioxygenase; chick yellow
MGI ID: MGI:3617203
Gene: Tdo2  Location: Chr3:81865719-81883035 bp, - strand  Genetic Position: Chr3, 35.97 cM
Pale yellow coat and cataracts in the Tdo2chky/Tdo2chky Tyrc/Tyrc mouse

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  Swiss
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsWhole exome sequencing of this spontaneous mutation shows it to be a C-to-T transition in the coding sequence in exon 9, which is a nonsense mutation predicted to result in a premature stop codon at arginine codon 282 (p.R282*). (J:181237, J:222308)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tdo2 Mutation:  31 strains or lines available
References
Original:  J:149273 Karst SY, et al., Chick yellow: Mutation on Chromosome 3 causing eye and coat color abnormalties. MGI Direct Data Submission. 2009;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory