Cntf^tm1Eas
Targeted Allele Detail

Summary

• Symbol: Cntf^tm1Eas
• Name: ciliary neurotrophic factor; targeted mutation 1, Esther Asan
• MGI ID: MGI:3615510
• Synonyms: CNTF-lacZ
• Gene: Cntf Location: Chr19:12741024-12742996 bp, - strand Genetic Position: Chr19, 8.73 cM
• Alliance: Cntf^tm1Eas page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:105479
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The beta galactosidase protein coding sequence as well as a pgk-neo cassette was introduced into the locus. Immunoreactivity was found for beta galactosidase in the narrow nuclei of olfactory nerve layer ensheathing cells, as expected according to endogenous Cntf activity in wild mice. (J:105479)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cntf Mutation: 16 strains or lines available

References

• Original: J:105479 Asan E, et al., Ciliary neurotrophic factor in the olfactory bulb of rats and mice. Neuroscience. 2003;120(1):99-112
• All: 2 reference(s)