Wnt3a^tm2Eag
Targeted Allele Detail

Summary

• Symbol: Wnt3a^tm2Eag
• Name: wingless-type MMTV integration site family, member 3A; targeted mutation 2, Elizabeth A Grove
• MGI ID: MGI:3612796
• Synonyms: Wnt3a-xneox-dt-a
• Gene: Wnt3a Location: Chr11:59138859-59181578 bp, - strand Genetic Position: Chr11, 37.17 cM
• Alliance: Wnt3a^tm2Eag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104373
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: An IRES-xneox-dt-a was inserted into the 3' end of the locus. The toxin remains inactive until removal of floxed stop codons. (J:104373)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wnt3a Mutation: 25 strains or lines available

References

• Original: J:104373 Yoshida M, et al., Massive loss of Cajal-Retzius cells does not disrupt neocortical layer order. Development. 2006 Feb;133(3):537-45
• All: 3 reference(s)