Jag1^tm1.1Vtlr
Targeted Allele Detail

Summary

• Symbol: Jag1^tm1.1Vtlr
• Name: jagged 1; targeted mutation 1.1, Verdon Taylor
• MGI ID: MGI:3612395
• Synonyms: Jag1^-
• Gene: Jag1 Location: Chr2:136923371-136958440 bp, - strand
• Alliance: Jag1^tm1.1Vtlr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103728
• Parent Cell Line: GS1 (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• The first two exons were deleted via cre-mediated recombination. (J:103728)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Jag1 Mutation: 76 strains or lines available

References

• Original: J:103728 Nyfeler Y, et al., Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal. EMBO J. 2005 Oct 5;24(19):3504-15
• All: 1 reference(s)