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Targeted Allele Detail
Symbol: Rasgrf1tm4.1Pds
Name: RAS protein-specific guanine nucleotide-releasing factor 1; targeted mutation 4.1, Paul D Soloway
MGI ID: MGI:3611767
Synonyms: Flox-R, Rasgrf1tm4Pds
Gene: Rasgrf1  Location: Chr9:89909908-90026977 bp, + strand  Genetic Position: Chr9, 47.31 cM
Germline Transmission:  Earliest citation of germline transmission: J:103751
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA targeting vector was designed to flank the direct repeat sequence downstream of the differentially methylated domain (DMD). A neomycin resistance cassette flanked by a FRT sites that was included downstream of the floxed sequence was removed via FLPe expression. (J:117666)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rasgrf1 Mutation:  10 strains or lines available
Original:  J:103751 Yoon B, et al., Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker. Mol Cell Biol. 2005 Dec;25(24):11184-90
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory