Rxrbtm1Pcn
Targeted Allele Detail
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Symbol: |
Rxrbtm1Pcn |
Name: |
retinoid X receptor beta; targeted mutation 1, Pierre Chambon |
MGI ID: |
MGI:3611570 |
Synonyms: |
RXRbetaL2 |
Gene: |
Rxrb Location: Chr17:34250786-34257373 bp, + strand Genetic Position: Chr17, 17.98 cM
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Alliance: |
Rxrbtm1Pcn page
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Rxratm4Ipc/Rxratm4Ipc Rxrbtm1Pcn/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 mice develop a chronic skin inflammation
Show the 4 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:102470
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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LoxP sites flank exons 3 and 4, which encode the B and C regions and the Nt amino acids of region D. (J:102470, J:109510)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rxrb Mutation: |
26 strains or lines available
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Original: |
J:102470 Li M, et al., Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14795-800 |
All: |
12 reference(s) |
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