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Angptl3tm1Akos
Targeted Allele Detail
Nomenclature
Symbol: Angptl3tm1Akos
Name: angiopoietin-like 3; targeted mutation 1, Anja Koster
MGI ID: MGI:3610614
Synonyms: Angptl3-
Gene: Angptl3  Location: Chr4:99030954-99046111 bp, + strand  Genetic Position: Chr4, 45.6 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:103363
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to remove 1.3 kb of sequence, including exon 1 containing the start codon. Northern blot failed to detect transcript in mutant liver tissue. (J:103363)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Angptl3 Mutation:  16 strains or lines available
References
Original:  J:103363 Koster A, et al., Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism. Endocrinology. 2005 Nov;146(11):4943-50
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory