About   Help   FAQ
Angptl3tm1Akos
Targeted Allele Detail
Nomenclature
Symbol: Angptl3tm1Akos
Name: angiopoietin-like 3; targeted mutation 1, Anja Koster
MGI ID: MGI:3610614
Synonyms: Angptl3-
Gene: Angptl3  Location: Chr4:99030954-99046111 bp, + strand  Genetic Position: Chr4, 45.6 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:103363
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to remove 1.3 kb of sequence, including exon 1 containing the start codon. Northern blot failed to detect transcript in mutant liver tissue. (J:103363)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Angptl3 Mutation:  16 strains or lines available
References
Original:  J:103363 Koster A, et al., Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism. Endocrinology. 2005 Nov;146(11):4943-50
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/18/2017
MGI 6.08
The Jackson Laboratory