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Apba1tm1Amor
Targeted Allele Detail
Nomenclature
Symbol: Apba1tm1Amor
Name: amyloid beta (A4) precursor protein binding, family A, member 1; targeted mutation 1, Atsushi Mori
MGI ID: MGI:3609568
Gene: Apba1  Location: Chr19:23758887-23949596 bp, + strand  Genetic Position: Chr19, 18.45 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:102794
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129S/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1.0-kb sequence containing the first methionine of the gene was replaced with the pMC1-neomycin-polyA cassette. Northern and Western blot analyses failed to detect transcript and protein, respectively, in mutant brain samples. (J:102794)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Apba1 Mutation:  3 strains or lines available
Notes
ES cell line = CCE28
References
Original:  J:102794 Mori A, et al., Alteration of methamphetamine-induced striatal dopamine release in mint-1 knockout mice. Neurosci Res. 2002 Jul;43(3):251-7
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory