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Kcnq2tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Kcnq2tm1Dgen
Name: potassium voltage-gated channel, subfamily Q, member 2; targeted mutation 1, Deltagen
MGI ID: MGI:3604594
Gene: Kcnq2  Location: Chr2:181075579-181135291 bp, - strand  Genetic Position: Chr2, 103.57 cM, cytoband H3-4
Mutation
origin
Mutant Cell Line:  5389 (Deltagen)
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA lacZ/IRES/neo cassette replaced sequences corresponding to bases 418 to 535 of the coding region. RT-PCR analysis detects a gene transcript at high levels in brain, spinal cord, pituitary gland and adrenal gland and at lower levels in eye, thymus, lymph nodes, gallbladder, stomach, small intestine, cecum, colon, testis, epididymis, prostate gland, ovary and white fat; beta-galactosidase expression is not detectable in any tissue. (J:142688)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 36 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kcnq2 Mutation:  9 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.

References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory