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Targeted Allele Detail
Symbol: Pkd2l2tm1Dgen
Name: polycystic kidney disease 2-like 2; targeted mutation 1, Deltagen
MGI ID: MGI:3604592
Gene: Pkd2l2  Location: Chr18:34541553-34575842 bp, + strand  Genetic Position: Chr18, 18.62 cM, cytoband C
Mutant Cell Line:  317
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Disruption caused by insertion of vector
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in ubcortical region, cerebellum, heart, pancreas, kidneys, spleen, thymus, lymph nodes, bone marrow and testis; beta-galactosidase expression is detectable in pancreas, testis and ovary.
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 50 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pkd2l2 Mutation:  28 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory