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Gpr151tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Gpr151tm1Dgen
Name: G protein-coupled receptor 151; targeted mutation 1, Deltagen
MGI ID: MGI:3604578
Gene: Gpr151  Location: Chr18:42578020-42579652 bp, - strand  Genetic Position: Chr18, 22.71 cM
Mutation
origin
Mutant Cell Line:  7935
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in the lymph nodes, moderate levels in cerebellum, olfactory bulb, spinal cord, Harderian glands, lung, liver, pancreas, skin, urinary bladder, pituitary gland, adrenal gland, tongue, stomach, small intestine, epididymis, coagulating gland, prostate gland, ovary and uterus and low levels in whole brain, cortex, subcortical region, brainstem, eye, heart, kidney, spleen, thymus, bone marrow, gallbladder, salivary gland, large intestine, cecum, testis, seminal vesicle and white fat. Beta-galactosidase expression from this allele is detectable only in brain. In the whole mount brain, moderate staining was observed in the thalamus and cerebellum with weak staining in the brainstem. On coronal sections, faint expression was detected in a few cells in the Purkinje cell layer of the cerebellum.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 36 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gpr151 Mutation:  5 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory