Faim2^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Faim2^tm1Dgen
• Name: Fas apoptotic inhibitory molecule 2; targeted mutation 1, Deltagen
• MGI ID: MGI:3604553
• Synonyms: LFG KO
• Gene: Faim2 Location: Chr15:99394893-99426046 bp, - strand Genetic Position: Chr15, 56.13 cM, cytoband F3
• Alliance: Faim2^tm1Dgen page

Mutation origin

• Mutant Cell Line: 3150
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects gene transcript in brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, spinal cord, eye, heart, lung, pancreas, kidney, thymus, lymph nodes, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, adrenal gland, salivary gland, skeletal muscle, tongue, stomach, small intestine, large intestine, cecum, testis, epididymis, seminal vesicle, coagulating gland, prostate gland, ovaries, uterus and white fat. Beta-galactosidase expression from this allele is detectable in brain. In wholemount staining lacZ expression is detectable in olfactory bulb, cortex, thalamus, hypothalamus and cerebellum. On coronal sections lacZ expression is detectable in cortex and hippocampus.

Expression

In Mice Carrying this Mutation:	23 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Faim2 Mutation: 22 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 4 reference(s)