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Targeted Allele Detail
Symbol: Ccr7tm1Dgen
Name: chemokine (C-C motif) receptor 7; targeted mutation 1, Deltagen
MGI ID: MGI:3604543
Gene: Ccr7  Location: Chr11:99035025-99045903 bp, - strand  Genetic Position: Chr11, 62.92 cM, cytoband D
Mutant Cell Line:  648
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA bacterial lacZ-neomycin fusion gene was inserted into the gene to replace a 608 bp portion of exon 3 of the gene , encoding thr-38 to glu-299, such that the endogenous gene promoter drives expression of beta-galactosidase. Beta-galactosidase expression from this allele is detectable in the immune system, including the spleen and lymph nodes and in coagulating glands of the male reproductive system. (J:135850)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 55 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ccr7 Mutation:  18 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory