Ccr7^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Ccr7^tm1Dgen
• Name: C-C motif chemokine receptor 7; targeted mutation 1, Deltagen
• MGI ID: MGI:3604543
• Gene: Ccr7 Location: Chr11:99035025-99045903 bp, - strand Genetic Position: Chr11, 62.92 cM, cytoband D
• Alliance: Ccr7^tm1Dgen page

Mutation origin

• Mutant Cell Line: 648
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A bacterial lacZ-neomycin fusion gene was inserted into the gene to replace a 608 bp portion of exon 3 of the gene , encoding thr-38 to glu-299, such that the endogenous gene promoter drives expression of beta-galactosidase. Beta-galactosidase expression from this allele is detectable in the immune system, including the spleen and lymph nodes and in coagulating glands of the male reproductive system. (J:135850)

Expression

In Mice Carrying this Mutation:	55 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ccr7 Mutation: 28 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 14 reference(s)