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Capn5tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Capn5tm1Dgen
Name: calpain 5; targeted mutation 1, Deltagen
MGI ID: MGI:3604529
Gene: Capn5  Location: Chr7:98121559-98178274 bp, - strand  Genetic Position: Chr7, 53.57 cM
Mutation
origin
Mutant Cell Line:  1385
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are detectable in salivary gland, subcortical region of the brain, cerebellum, brainstem, olfactory bulb, spinal cord, eye, Harderian glands, lung, liver, pancreas, kidney, spleen, thymus, bone marrow, skin, gallbladder, urinary bladder, stomach, large intestine, cecum, epididymis, seminal vesicle, coagulating gland, prostate gland, ovaries and uterus. Striking lacZ (beta-galactosidase) expression is detectable in brain, spinal cord and ganglia. Other tissues displaying X-Gal staining are kidney, urinary bladder, salivary glands, and male reproductive system.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 112 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Capn5 Mutation:  36 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory