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Htr1ftm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Htr1ftm1Dgen
Name: 5-hydroxytryptamine (serotonin) receptor 1F; targeted mutation 1, Deltagen
MGI ID: MGI:3604523
Gene: Htr1f  Location: Chr16:64924729-65105784 bp, - strand  Genetic Position: Chr16, 37.1 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. Low levels of RNA transcripts are detectable in brain, cortex, subcortical region, brainstem, olfactory bulb, large intestine, cecum and testis. No RNA transcripts are detectable in cerebellum, spinal cord, eye, Harderian glands, heart, lung, liver, pancreas, kidney, spleen, thymus, lymph nodes, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, adrenal gland, salivary gland, skeletal muscle, tongue, stomach, small intestine, epididymis, seminal vesicle, coagulating gland, prostate gland, ovaries, uterus and white fat. LacZ (beta-galactosidase) expression is detectable in brain, spinal cord, pituitary gland and testis. Most striking expression is observed in brain.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 61 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Htr1f Mutation:  14 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory