Mmp16^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Mmp16^tm1Dgen
• Name: matrix metallopeptidase 16; targeted mutation 1, Deltagen
• MGI ID: MGI:3604479
• Gene: Mmp16 Location: Chr4:17853072-18117479 bp, + strand Genetic Position: Chr4, 7.08 cM
• Alliance: Mmp16^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in brain, spinal cord and pituitary gland and at lower levels in cerebellum, brainstem, eye, Harderian glands, heart, lung, pancreas, kidney, spleen, lymph nodes, gallbladder, urinary bladder, adrenal gland, tongue, stomach, small intestine, large intestine, testis, epididymis, seminal vesicle, prostate gland, ovary, uterus and white fat; beta-galactosidase expression is detectable in brain, spinal cord, eyes, aorta, heart, lung, urinary bladder, thyroid gland, parathyroid gland, trachea, pituitary gland, adrenal glands, skin, prostate gland, ovary and uterus.

Expression

In Mice Carrying this Mutation:

60 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mmp16 Mutation: 43 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 2 reference(s)