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Targeted Allele Detail
Symbol: Mmp16tm1Dgen
Name: matrix metallopeptidase 16; targeted mutation 1, Deltagen
MGI ID: MGI:3604479
Gene: Mmp16  Location: Chr4:17853072-18117479 bp, + strand  Genetic Position: Chr4, 7.08 cM
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Disruption caused by insertion of vector
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in brain, spinal cord and pituitary gland and at lower levels in cerebellum, brainstem, eye, Harderian glands, heart, lung, pancreas, kidney, spleen, lymph nodes, gallbladder, urinary bladder, adrenal gland, tongue, stomach, small intestine, large intestine, testis, epididymis, seminal vesicle, prostate gland, ovary, uterus and white fat; beta-galactosidase expression is detectable in brain, spinal cord, eyes, aorta, heart, lung, urinary bladder, thyroid gland, parathyroid gland, trachea, pituitary gland, adrenal glands, skin, prostate gland, ovary and uterus.
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 60 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mmp16 Mutation:  28 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.19
The Jackson Laboratory