Prss12^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Prss12^tm1Dgen
• Name: serine protease 12 neurotrypsin (motopsin); targeted mutation 1, Deltagen
• MGI ID: MGI:3604467
• Gene: Prss12 Location: Chr3:123240562-123300246 bp, + strand Genetic Position: Chr3, 54.58 cM, cytoband G3
• Alliance: Prss12^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RNA transcripts are detected in lung, pancreas, gallbladder, adrenal gland, skeletal muscle and reproductive organs, beta-galactosidase expression from this allele is detectable in brain, spinal cord, sciatic nerve, lymph nodes, kidney, urinary bladder, skeletal muscle, skin, testis, ovary and cervix.

Expression

In Mice Carrying this Mutation:

42 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prss12 Mutation: 36 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 1 reference(s)