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Targeted Allele Detail
Symbol: Prss12tm1Dgen
Name: protease, serine 12 neurotrypsin (motopsin); targeted mutation 1, Deltagen
MGI ID: MGI:3604467
Gene: Prss12  Location: Chr3:123446913-123506597 bp, + strand  Genetic Position: Chr3, 54.58 cM, cytoband G3
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RNA transcripts are detected in lung, pancreas, gallbladder, adrenal gland, skeletal muscle and reproductive organs, beta-galactosidase expression from this allele is detectable in brain, spinal cord, sciatic nerve, lymph nodes, kidney, urinary bladder, skeletal muscle, skin, testis, ovary and cervix.
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 42 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prss12 Mutation:  21 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory