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Targeted Allele Detail
Symbol: Rgs5tm1Dgen
Name: regulator of G-protein signaling 5; targeted mutation 1, Deltagen
MGI ID: MGI:3604464
Gene: Rgs5  Location: Chr1:169483070-169523382 bp, + strand  Genetic Position: Chr1, 76.84 cM, cytoband H2
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a gene transcript in many of the tissues analyzed, beta-galactosidase expression from this allele is detectable in brain, spinal cord, sciatic nerve, eyes, thymus, spleen, lymph nodes, aorta, heart, lung, liver, pancreas, kidney, urinary bladder, thyroid gland, pituitary gland, adrenal glands, skeletal muscle, skin, ad reproductive organs but not in bone marrow.
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 76 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Rgs5 Mutation:  17 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.20
The Jackson Laboratory