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Targeted Allele Detail
Symbol: Creb3l4tm1Imad
Name: cAMP responsive element binding protein 3-like 4; targeted mutation 1, Ibrahim M Adham
MGI ID: MGI:3589381
Synonyms: Creb3l4-
Gene: Creb3l4  Location: Chr3:90237500-90243512 bp, - strand  Genetic Position: Chr3, 39.21 cM
Germline Transmission:  Earliest citation of germline transmission: J:100527
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA 4.0-kb fragment of sequence encompassing exons 1a to 4 was replaced with GFP and a PGK-neomycin resistance cassette. Testes were analyzed by Northern blot, revealing no expression in mutants. GFP expression, however, was detected strongly in adult testes. (J:100527)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Creb3l4 Mutation:  7 strains or lines available
Original:  J:100527 Adham IM, et al., Reduction of spermatogenesis but not fertility in Creb3l4-deficient mice. Mol Cell Biol. 2005 Sep;25(17):7657-64
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory