Dnmt1^MommeD2
Chemically induced Allele Detail

Summary

• Symbol: Dnmt1^MommeD2
• Name: DNA methyltransferase 1; modifiers of murine metastable epiallele D2
• MGI ID: MGI:3586549
• Gene: Dnmt1 Location: Chr9:20818501-20871084 bp, - strand Genetic Position: Chr9, 7.66 cM
• Alliance: Dnmt1^MommeD2 page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Mice carrying Tg(Hba1-Gfp)1Ew were treated with ENU. A C to A transversion in exon 25 results in a T to K amino acid residue change in the proximal bromo-adjacent homology domain. (J:122400)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnmt1 Mutation: 108 strains or lines available

References

• Original: J:99816 Blewitt ME, et al., An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse. Proc Natl Acad Sci U S A. 2005 May 24;102(21):7629-34
• All: 6 reference(s)