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Dad1tm1Kni
Targeted Allele Detail
Nomenclature
Symbol: Dad1tm1Kni
Name: defender against cell death 1; targeted mutation 1, Kiyomasa Nishii
MGI ID: MGI:3586491
Synonyms: Dad1-
Gene: Dad1  Location: Chr14:54235479-54254104 bp, - strand  Genetic Position: Chr14, 27.7 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99897
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsThe insertion of a neo at amino acid 18, upstream from the first membrane-spanning domain, disrupted the ORF. (J:99897)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dad1 Mutation:  7 strains or lines available
References
Original:  J:99897 Nishii K, et al., Abnormalities of developmental cell death in Dad1-deficient mice. Genes Cells. 1999 Apr;4(4):243-52
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory