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Xisttm2Sado
Targeted Allele Detail
Nomenclature
Symbol: Xisttm2Sado
Name: inactive X specific transcripts; targeted mutation 2, Takashi Sado
MGI ID: MGI:3583750
Synonyms: Xist1lox
Gene: Xist  Location: ChrX:103460373-103483233 bp, - strand  Genetic Position: ChrX, 46.15 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99399
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsThe same targeting vector for Xisttm1Sado was inserted into normal ES cells, thereby replacing part of exon 1 with an IRES-EGFP cassette such that the reporter is under the control of the endogenous promoter. (J:99399)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Xist Mutation:  5 strains or lines available
References
Original:  J:99399 Sado T, et al., Tsix Silences Xist through Modification of Chromatin Structure. Dev Cell. 2005 Jul;9(1):159-165
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2020
MGI 6.16
The Jackson Laboratory