Tg(Tcra,Tcrb)1Mcd
Transgene Detail

Summary

• Symbol: Tg(Tcra,Tcrb)1Mcd
• Name: transgene insertion 1, Hugh O McDevitt
• MGI ID: MGI:3581980
• Synonyms: HNT, HNT TCR, HNT-TCR, TCR-HNT, TCR Tg, TS2, Valpha15 Vbeta8.3 HNT TCR
• Transgene: Tg(Tcra,Tcrb)1Mcd Location: unknown
• Alliance: Tg(Tcra,Tcrb)1Mcd page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Tcra,Tcrb)1Mcd expresses 2 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tcra (MGI:98553)
  mouse	Tcrb (MGI:98578)

• Mutation details: These mice were generated using TCRalpha and TCRbeta shuttle vectors and express the receptor genes specific for hemagglutinin peptide 126-138. (J:99315)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:99315 Scott B, et al., A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity. Immunity. 1994 Apr;1(1):73-83
• All: 14 reference(s)