About   Help   FAQ
Transgene Detail
Symbol: Tg(GFAP)10Mes
Name: transgene insertion 10, Albee Messing
MGI ID: MGI:3581819
Synonyms: GFAPTg, TgN(GFAP)Mes10
Transgene: Tg(GFAP)10Mes  Location: unknown  
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(GFAP)10Mes expresses 1 gene
Mutation detailsThis transgene consists of a 17.5 kb fragment of DNA extending about 6 kb upstream to 1.5 kb downstream of the human GFAP gene, including regulatory elements sufficient to direct astrocyte-specific expression. Five lines were established 2 of which had high levels of expression in at least some mice (73.1 uniformly high expression and 73.7 about 20% with high expression). Line 73.7 was given a strain designation TgN(GFAP)Mes10. This is the representative record for both high expressing lines. (J:99256)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:99256 Messing A, et al., Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice. Am J Pathol. 1998 Feb;152(2):391-8
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.19
The Jackson Laboratory