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Transgene Detail
Symbol: Tg(GFAP)10Mes
Name: transgene insertion 10, Albee Messing
MGI ID: MGI:3581819
Synonyms: GFAPTg, TgN(GFAP)Mes10
Transgene: Tg(GFAP)10Mes  Location: unknown  
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(GFAP)10Mes expresses 1 gene
Mutation detailsThis transgene consists of a 17.5 kb fragment of DNA extending about 6 kb upstream to 1.5 kb downstream of the human GFAP gene, including regulatory elements sufficient to direct astrocyte-specific expression. Five lines were established 2 of which had high levels of expression in at least some mice (73.1 uniformly high expression and 73.7 about 20% with high expression). Line 73.7 was given a strain designation TgN(GFAP)Mes10. This is the representative record for both high expressing lines. (J:99256)
View phenotypes for all genotypes (concatenated display).
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:99256 Messing A, et al., Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice. Am J Pathol. 1998 Feb;152(2):391-8
All:  6 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory