Rr27tm3Tilg
Targeted Allele Detail
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Symbol: |
Rr27tm3Tilg |
Name: |
regulatory region 27; targeted mutation 3, Shirley M Tilghman |
MGI ID: |
MGI:3580481 |
Synonyms: |
H19Ku site-, H19tm5Tilg |
Gene: |
Rr27 Location: unknown Genetic Position: Chr7, Syntenic
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Alliance: |
Rr27tm3Tilg page
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Germline Transmission: |
Earliest citation of germline transmission:
J:98880
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Parent Cell Line: |
AB2.2 (ES Cell)
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Strain of Origin: |
129S7/SvEvBrd-Hprt1b-m2
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Allele Type: |
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Targeted (Modified regulatory region) |
Mutation: |
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Insertion
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Mutation details: Mutations to change the ATCGAT to CACGCA were introduced into the DNA binding sites of hypersensitivity sites 1 and 2 of the imprinting control region. A loxP site flanked neomycin resistance gene was excised upon expression of cre recombinase in testes.
(J:98880)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rr27 Mutation: |
6 strains or lines available
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Original: |
J:98880 Katz DJ, et al., Functional characterization of a novel Ku70/80 pause site at the H19/Igf2 imprinting control region. Mol Cell Biol. 2005 May;25(10):3855-63 |
All: |
1 reference(s) |
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