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L3mbtl3tm1Tmiy
Targeted Allele Detail
Nomenclature
Symbol: L3mbtl3tm1Tmiy
Name: L3MBTL3 histone methyl-lysine binding protein; targeted mutation 1, Toru Miyazaki
MGI ID: MGI:3579468
Synonyms: MTB-1-
Gene: L3mbtl3  Location: Chr10:26274468-26375971 bp, - strand  Genetic Position: Chr10, 13.67 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98498
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene replaced exon 15. Northern blot of mutant liver demonstrated the complete lack of transcript. (J:98498)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any L3mbtl3 Mutation:  34 strains or lines available
References
Original:  J:98498 Arai S, et al., Impaired maturation of myeloid progenitors in mice lacking novel Polycomb group protein MBT-1. EMBO J. 2005 May 18;24(10):1863-73
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory