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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		L3mbtl3tm1Tmiy
targeted mutation 1, Toru Miyazaki
MGI:3579468
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		L3mbtl3tm1Tmiy/L3mbtl3tm1Tmiy Not Specified MGI:3580779


Genotype
MGI:3580779
hm1
Allelic
Composition		 L3mbtl3tm1Tmiy/L3mbtl3tm1Tmiy
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
L3mbtl3tm1Tmiy mutation (1 available); any L3mbtl3 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
perinatal lethality, complete penetrance ( J:98498 )
• died during a late embryonic stage between E17.5 and E19.5

hematopoietic system
abnormal definitive hematopoiesis ( J:98498 )
• myeloid progenitor cells exhibit a maturational deficiency but maintain normal proliferative activities, resulting in decrease in mature myeloid lineage cells in fetal liver
anemia ( J:98498 )
• a marked decrease of mature myeloid blood cells due to myeloid progenitor cells maturational deficiency




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory