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Festm2Pag
Targeted Allele Detail
Nomenclature
Symbol: Festm2Pag
Name: feline sarcoma oncogene; targeted mutation 2, Peter A Greer
MGI ID: MGI:3578748
Synonyms: fps-
Gene: Fes  Location: Chr7:80377758-80387946 bp, - strand  Genetic Position: Chr7, 45.65 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98590
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 15 through 18 were replaced with a PGKneo cassette via homologous recombination. (J:98590)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fes Mutation:  1 strain or line available
References
Original:  J:98590 Zirngibl RA, et al., Enhanced endotoxin sensitivity in fps/fes-null mice with minimal defects in hematopoietic homeostasis. Mol Cell Biol. 2002 Apr;22(8):2472-86
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory