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Rbbp8tm1Whl
Targeted Allele Detail
Nomenclature
Symbol: Rbbp8tm1Whl
Name: retinoblastoma binding protein 8, endonuclease; targeted mutation 1, Wen-Hwa Lee
MGI ID: MGI:3577029
Synonyms: Ctip-
Gene: Rbbp8  Location: Chr18:11633276-11743207 bp, + strand  Genetic Position: Chr18, 5.85 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97648
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA PGK-NeopA was inserted into exon 5 at the position equivalent to amino acid residue 109 in the human protein. (J:97648)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rbbp8 Mutation:  25 strains or lines available
References
Original:  J:97648 Chen PL, et al., Inactivation of CtIP Leads to Early Embryonic Lethality Mediated by G1 Restraint and to Tumorigenesis by Haploid Insufficiency. Mol Cell Biol. 2005 May;25(9):3535-42
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory