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Tg(Agrp-cre)1Gsb
Transgene Detail
Nomenclature
Symbol: Tg(Agrp-cre)1Gsb
Name: transgene insertion 1, Gregory S Barsh
MGI ID: MGI:3576074
Synonyms: AGRP-Cre, Tg.AgrpCre, Tg.AgRP-Cre
Transgene: Tg(Agrp-cre)1Gsb  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsCre recombinase cDNA with an IVSpA sequence was placed immediately upstream of the normal translational initiation site in exon 2 of Agrp in a BAC clone. Cre was expressed in the medial portion of the arcuate nucleus of mutant brains. (J:97407)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Agrp     Summary of all recombinase alleles driven by Agrp.
 

Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:97407 Xu AW, et al., PI3K integrates the action of insulin and leptin on hypothalamic neurons. J Clin Invest. 2005 Apr 1;115(4):951-958
All:  34 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory