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SryAKR/J
Spontaneous Allele Detail
Nomenclature
Symbol: SryAKR/J
Name: sex determining region of Chr Y; sex-determining region of Chr Y- AKR/J
MGI ID: MGI:3575651
Synonyms: AKR YDOM, YAKR
Gene: Sry  Location: ChrY:2662471-2663658 bp, - strand  Genetic Position: ChrY, cytoband p
Ovotestis development in Map3k4tm1Flv/Map3k4+ X/SryAKR/J embryos, characterised by gonadal poles (brackets) lacking markers of testis development and expressing markers of ovary development

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  AKR/J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Undefined
 
Mutation detailsThis allele contains all the information necessary and sufficient to initiate normal testis development but is conditionally dysfunctional on the C57BL/6 background. (J:44538)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 6 strains available      Cell Lines: 0 lines available
Carrying any Sry Mutation:  34 strains or lines available
References
Original:  J:10075 Washburn LL, et al., Normal testis determination in the mouse depends on genetic interaction of a locus on chromosome 17 and the Y chromosome. Genetics. 1989 Sep;123(1):173-9
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory