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Bmpr2tm1.2Enl
Targeted Allele Detail
Nomenclature
Symbol: Bmpr2tm1.2Enl
Name: bone morphogenetic protein receptor, type II (serine/threonine kinase); targeted mutation 1.2, En Li
MGI ID: MGI:3574813
Synonyms: BMPR-II1loxP
Gene: Bmpr2  Location: Chr1:59763400-59879014 bp, + strand  Genetic Position: Chr1, 30.44 cM, cytoband C2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97109
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsBmpr2tm1.1Enl were crossed with EIIa-cre mice to remove exons 4 and 5. This deletion created a frame shift in exon 6, with the first stop codon following 11 missense amino acids. (J:97109)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bmpr2 Mutation:  25 strains or lines available
References
Original:  J:97109 Beppu H, et al., Generation of a floxed allele of the mouse BMP type II receptor gene. Genesis. 2005 Mar;41(3):133-7
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory