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Txniptm1Yu
Targeted Allele Detail
Nomenclature
Symbol: Txniptm1Yu
Name: thioredoxin interacting protein; targeted mutation 1, Dae-Yeul Yu
MGI ID: MGI:3574362
Synonyms: VDUP1-
Gene: Txnip  Location: Chr3:96557957-96561883 bp, + strand  Genetic Position: Chr3, 41.93 cM, cytoband F2.2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96677
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe sequence from exon 1 to 8 was replaced by a lacZ and neo. RT-PCR and Northern blot confirmed absence of transcript in mutant tissues. (J:96677)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Txnip Mutation:  34 strains or lines available
References
Original:  J:96677 Lee KN, et al., VDUP1 is required for the development of natural killer cells. Immunity. 2005 Feb;22(2):195-208
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory