About   Help   FAQ
Txniptm1Yu
Targeted Allele Detail
Nomenclature
Symbol: Txniptm1Yu
Name: thioredoxin interacting protein; targeted mutation 1, Dae-Yeul Yu
MGI ID: MGI:3574362
Synonyms: VDUP1-
Gene: Txnip  Location: Chr3:96557957-96561883 bp, + strand  Genetic Position: Chr3, 41.93 cM, cytoband F2.2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96677
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe sequence from exon 1 to 8 was replaced by a lacZ and neo. RT-PCR and Northern blot confirmed absence of transcript in mutant tissues. (J:96677)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Txnip Mutation:  37 strains or lines available
References
Original:  J:96677 Lee KN, et al., VDUP1 is required for the development of natural killer cells. Immunity. 2005 Feb;22(2):195-208
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/12/2017
MGI 6.10
The Jackson Laboratory