Pknox1Gt(OST71835)Lex
Gene trapped Allele Detail
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Symbol: |
Pknox1Gt(OST71835)Lex |
Name: |
Pbx/knotted 1 homeobox; gene trap OST71835, Lexicon Genetics |
MGI ID: |
MGI:3530910 |
Synonyms: |
Pknox1Gt(neo)628Lex, Prep1i |
Gene: |
Pknox1 Location: Chr17:31564734-31607693 bp, + strand Genetic Position: Chr17, 16.78 cM, cytoband B-C
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Mutant Cell Line: |
OST71835 |
Germline Transmission: |
Earliest citation of germline transmission:
J:103485
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Parent Cell Line: |
Lex-1 (ES Cell)
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Strain of Origin: |
129S5/SvEvBrd
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Project Collection: |
Lexicon |
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Allele Type: |
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Gene trapped (Hypomorph) |
Mutation: |
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Insertion of gene trap vector
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Mutation details: The clone used for gene trapping was isolated from a library of embryonic stem cells randomly targeted with the retroviral vector VICTR45 using an enhancer trap strategy. Retroviral insertion occurred at nucleotide 849 of intron 1 located within the 5' untranslated region (2.8 kb from the ATG). RT-PCR analysis revealed that transcript was absent in most homozygous mice. However, in some homozygotes a low level of protein (about 5-10% of wild-type) is detected.
(J:103485, J:103769, J:111418)
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Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
Blue line marks
approximate position of gene trap insertion

223 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
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View phenotypes and curated references for all genotypes (concatenated display).
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See also, data as provided by Lexicon Genetics, Inc.
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Original: |
J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005; |
All: |
19 reference(s) |
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