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NplGt(OST15553)Lex
Gene trapped Allele Detail
Nomenclature
Symbol: NplGt(OST15553)Lex
Name: N-acetylneuraminate pyruvate lyase; gene trap OST15553, Lexicon Genetics
MGI ID: MGI:3530042
Synonyms: NplGt(IRESBetageo)332Lex
Gene: Npl  Location: Chr1:153503015-153550045 bp, - strand  Genetic Position: Chr1, 65.38 cM, cytoband G2
Mutation
origin
Mutant Cell Line:  OST15553
Germline Transmission:  Earliest citation of germline transmission: J:103485
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector
 
Mutation detailsRetroviral insertion occurred in the intron between exons 10 and 11. RT-PCR analysis revealed that the transcript was absent in homozygous mice. (J:103485)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 1 line available
Carrying any Npl Mutation:  37 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/05/2018
MGI 6.12
The Jackson Laboratory