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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		NplGt(OST15553)Lex
gene trap OST15553, Lexicon Genetics
MGI:3530042
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		NplGt(OST15553)Lex/NplGt(OST15553)Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:3609910


Genotype
MGI:3609910
hm1
Allelic
Composition		 NplGt(OST15553)Lex/NplGt(OST15553)Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NplGt(OST15553)Lex mutation (2 available); any Npl mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:202156 )
N
• mice exhibit normal reproduction

homeostasis/metabolism
increased circulating cholesterol level ( J:103485 )
• increased mean serum cholesterol levels

immune system
immune system phenotype ( J:103485 )
N
• numerous immunological abnormalities are seen

embryo
embryo phenotype ( J:202156 )
N
• embryos exhibit normal implantation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory